Since 2012, clinical studies on HOWARU® strains are conducted under ICH GCP guidelines to ensure the highest scientific and ethical standards, the same thorough standards as pharmaceutical prescription and over-the-counter brands. All IFF sponsored clinical trials are registered in trial registries such as ClinicalTrials.gov.
HOWARU® strains are featured in over 600 publications in leading journals such as Nature Medicine, Archives of Gynecology & Obstetrics, Journal of Gastroenterology, and Journal of Clinical Immunology. Select HOWARU® strains have been independently reviewed and included in the World Gastroenterology Organisation’s Global Guidelines and the Alliance for Education on Probiotics’ Clinical Guide to Probiotic Products Available in USA for various health benefits.
HOWARU® signature strains are rigorously evaluated through our 8-point verification protocol to ensure efficacy, safety, quality, and stability.
Recent publications from IFF scientists
GCP=Good Clinical Practice; ICH= International Council for Harmonisation of Technical Requirements for Pharmaceuticals for Human Use.
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